Israel's defence minister has threatened to destroy Syria's air defence systems if they are used to target Israeli fighter jets again.
This account was promptly disputed by the Israelis, who claimed that none of their planes were damaged.
In recent years, both Israeli and foreign media have reported a number of Israeli air strikes inside Syria targeting arms convoys of Lebanese militant group Hezbollah.
In the aftermath of Israel's early Friday morning airstrikes against Hezbollah targets in Syria, the country's Arrow anti-ballistic missile scored its first operational intercept - but against what, experts here are asking? The advanced program is set to intercept long-range missiles, working in combination with Iron Dome, which is created to protect from short-range threats, and other defense programs.
"When we identify attempts to transfer advanced weapons to Hezbollah and we have intelligence and it is operationally feasible, we act to prevent it", according to the Times of Israel.
An Israeli drone on Sunday reportedly struck a vehicle on a road in Syria between the suburbs of Quneitra near the Israeli border and Damascus, killing the driver, according to the Syrian Observatory for Human Rights.
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However, Arrow is created to intercept long-range ballistic missiles high in the stratosphere, so it remained unclear why the system would have been used in this particular incident.
The firing of missiles from Syria toward Israeli aircraft is extremely rare, though Israeli military officials reported a shoulder-fired missile a few months ago.
The Syrian military said the jets struck a military site near Palmyra, while Israel says they targeted a weapons shipment to Iran-backed Hezbollah.
In highly unusual comments confirming the operation, Israeli Prime Minister Benjamin Netanyahu said: "Our policy is very consistent".
Syria accused Israel of supporting the Islamic State. The Israeli army did not reveal the target of its overnight airstrikes. Debris from the missiles, which were intercepted by the Arrow Defence system over Jordan, landed on residential homes in the west of that country near Inba and Irbid.
Since the outbreak of the Syria conflict in 2011, Israel has occasionally struck positions inside its war-ravaged neighbor, especially after mortar shells - allegedly fired from Syrian territory - fell inside the Israeli-occupied Golan Heights.