Asked if that would be a ideal finale for the veteran striker, who is yet to confirm whether he will remain at Old Trafford for a second season, Mourinho said: 'I don't think about it, I just think about Manchester United. I am not saying he is old, we have older players, there are many older players in great conditions, but when you get to a certain age, it is a little bit more hard to recover.
"He had not big problems during the season, but a few small problems and sometimes when you get into a certain age - I am not saying he is old, we have older players, there are many older players in great condition - but when you get to a certain age, it is a little bit more hard to recover". I have confidence in every single player in the squad.
United are hoping to reach the Europa League final on 24 May at Stockholm's Friends Arena - where Ibrahimovic is having a statue erected in his honour.
Sir Alex Ferguson was at the helm when United last lost a continental match on home soil and Anderlecht have never won any of their 17 previous visits to English clubs, highlighting what a big ask lies in wait for the visitors.
Manchester United (ENG) v Anderlecht (BEL) (1-1).
The match will take place at Old Trafford.More news: Adidas sorry for email saying 'you survived' Boston Marathon
"I am not happy if he leaves, but he is the only player that I am informed has a possibility of leaving".
"I think it's just that, but we have seven matches to play in the Premier League, plus one or three or four in the Europa League, so we can go to 10 or 11 matches". It would be the ideal end to the season for us, a hard season with lots of matches. "That goal gives us extra motivation".
"So far has been okay for me but I still have to show I can give more", he told United Review.
"He's about that. It's about getting to know each other better and better and better and going in the direction of things we like. Manchester United were really strong and very impressive", he said.
Last week's first leg was delayed by 45 minutes after fans clashed at Parc OL and Lyon's league game at Bastia last weekend was called off following a shocking attack on their players by rival supporters. They could face Spanish team Celta Vigo, Dutch giants Ajax or French side Lyon in the semi-finals.